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Magnus Ingelman-Sundberg Selected Research

Cytochrome P-450 Enzyme System (Cytochrome P450)

1/2021Toward predicting CYP2D6-mediated variable drug response from CYP2D6 gene sequencing data.
7/2020Potential role of gut microbiota, the proto-oncogene PIKE (Agap2) and cytochrome P450 CYP2W1 in promotion of liver cancer by alcoholic and nonalcoholic fatty liver disease and protection by dietary soy protein.
2/2016Membrane topology and search for potential redox partners of colon cancer-specific cytochrome P450 2W1.
1/2016Human Cytochrome P450 2W1 Is Not Expressed in Adrenal Cortex and Is Only Rarely Expressed in Adrenocortical Carcinomas.
1/2015Developmental regulation and induction of cytochrome P450 2W1, an enzyme expressed in colon tumors.
7/2014The expression of CYP2W1 in colorectal primary tumors, corresponding lymph node metastases and liver metastases.
6/2013Colon cancer-specific cytochrome P450 2W1 converts duocarmycin analogues into potent tumor cytotoxins.
1/2013Update on allele nomenclature for human cytochromes P450 and the Human Cytochrome P450 Allele (CYP-allele) Nomenclature Database.
9/2012The expression of CYP2W1: a prognostic marker in colon cancer.
12/2010Colorectal cancer-specific cytochrome P450 2W1: intracellular localization, glycosylation, and catalytic activity.
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Magnus Ingelman-Sundberg Research Topics

Disease

26Drug-Related Side Effects and Adverse Reactions
07/2021 - 01/2004
24Neoplasms (Cancer)
11/2022 - 03/2002
19Hepatocellular Carcinoma (Hepatoma)
01/2020 - 03/2003
10Liver Diseases (Liver Disease)
10/2022 - 08/2013
9Carcinogenesis
07/2021 - 02/2003
8Lung Neoplasms (Lung Cancer)
05/2008 - 05/2002
7Colonic Neoplasms (Colon Cancer)
02/2016 - 10/2007
6Colorectal Neoplasms (Colorectal Cancer)
01/2016 - 03/2009
6Genetic Predisposition to Disease (Genetic Predisposition)
01/2015 - 08/2002
5Breast Neoplasms (Breast Cancer)
01/2021 - 04/2003
5Chemical and Drug Induced Liver Injury
01/2018 - 11/2008
4Alcoholic Liver Diseases (Alcoholic Liver Disease)
07/2021 - 04/2004
4Fatty Liver
07/2020 - 03/2008
4Inflammation (Inflammations)
09/2010 - 04/2004
4Necrosis
03/2008 - 04/2004
3Fibrosis (Cirrhosis)
01/2022 - 01/2020
3Liver Neoplasms (Liver Cancer)
07/2021 - 10/2002
2Alcoholic Fatty Liver
01/2022 - 01/2020
2Psychotic Disorders (Schizoaffective Disorder)
01/2021 - 01/2020
2Non-alcoholic Fatty Liver Disease
07/2020 - 12/2019
2Cholestasis
10/2018 - 10/2016
2Adrenocortical Carcinoma
01/2016 - 01/2016
2Neoplasm Metastasis (Metastasis)
01/2016 - 07/2014
2Infections
08/2013 - 02/2011
1Metaplasia
10/2022
1Hepatitis
01/2022
1Malaria
01/2022
1Dysbiosis
07/2020
1Liver Cirrhosis (Hepatic Cirrhosis)
01/2020
1Mitochondrial Diseases (Mitochondrial Disease)
08/2019
1Metabolic Syndrome (Dysmetabolic Syndrome X)
01/2019
1Rhabdomyosarcoma
01/2016
1Myotoxicity
10/2015
1Hypercholesterolemia
10/2015

Drug/Important Bio-Agent (IBA)

49Pharmaceutical PreparationsIBA
10/2022 - 01/2004
27EnzymesIBA
07/2021 - 03/2002
19Cytochrome P-450 Enzyme System (Cytochrome P450)IBA
01/2021 - 09/2003
9Proteins (Proteins, Gene)FDA Link
10/2022 - 07/2002
8Cytochrome P-450 CYP2E1 (CYP2E1)IBA
07/2021 - 07/2002
7Ethanol (Ethyl Alcohol)IBA
07/2020 - 02/2003
6Cytochrome P-450 CYP3AIBA
01/2020 - 12/2005
5Biomarkers (Surrogate Marker)IBA
10/2022 - 06/2004
5Messenger RNA (mRNA)IBA
07/2020 - 09/2005
5ProdrugsIBA
01/2016 - 12/2010
5DuocarmycinsIBA
01/2015 - 06/2013
5Cytochrome P-450 CYP1A1 (CYP1A1)IBA
08/2013 - 05/2003
5CytochromesIBA
03/2011 - 12/2002
5CarcinogensIBA
01/2010 - 08/2002
4AntibodiesIBA
01/2016 - 04/2004
4CytokinesIBA
11/2010 - 03/2003
4Transcription Factors (Transcription Factor)IBA
06/2010 - 04/2004
4Environmental CarcinogensIBA
12/2005 - 08/2002
4Estrogens (Estrogen)FDA Link
01/2005 - 04/2003
3LuciferasesIBA
11/2010 - 02/2004
3Hormones (Hormone)IBA
01/2005 - 09/2003
2Antipsychotic Agents (Antipsychotics)IBA
01/2021 - 01/2020
2NitritesIBA
01/2019 - 07/2002
2(5- chloro- 1H- indol- 2- yl)(1- (chloromethyl)- 1,2- dihydropyrrolo(3,2- e)indol- 3(6H)- yl)methanoneIBA
10/2013 - 06/2013
2Cytochrome P-450 CYP2C19IBA
11/2010 - 05/2010
2Cytochrome P-450 CYP1A2 (CYP1A2)IBA
06/2009 - 09/2003
2Reactive Oxygen Species (Oxygen Radicals)IBA
03/2009 - 06/2004
2AutoantibodiesIBA
11/2008 - 02/2003
2ChemokinesIBA
09/2008 - 03/2008
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
03/2008 - 09/2005
2NicotineFDA Link
02/2006 - 10/2002
2Polychlorinated Dibenzodioxins (TCDD)IBA
01/2005 - 09/2003
2Free RadicalsIBA
06/2004 - 02/2003
1Complement System Proteins (Complement)IBA
11/2022
1Acetaminophen (Paracetamol)FDA LinkGeneric
07/2021
1Oxygen (Dioxygen)IBA
07/2021
1Anesthetics (Anesthetic Agents)IBA
07/2021
1Cytochrome P-450 CYP2D6 (CYP2D6)IBA
01/2021
1TamoxifenFDA LinkGeneric
01/2021
1Corn Oil (Oil, Corn)IBA
07/2020
1Caseins (Casein)FDA Link
07/2020
1Soybean Proteins (Soy Protein)IBA
07/2020
1cocoa butterIBA
07/2020
1Olive OilIBA
07/2020
1Diethylnitrosamine (N-Nitrosodiethylamine)IBA
07/2020
1Dietary ProteinsIBA
07/2020
1Dietary Fats (Dietary Fat)IBA
07/2020
1Apolipoproteins B (ApoB)IBA
12/2019
1Mitochondrial DNA (mtDNA)IBA
08/2019
1fialuridineIBA
08/2019
1NitratesIBA
01/2019
1NADPH Oxidases (NAD(P)H oxidase)IBA
01/2019
1NG-Nitroarginine Methyl Ester (L-NAME)IBA
01/2019
1AMP-Activated Protein KinasesIBA
01/2019
1Nitric Oxide (Nitrogen Monoxide)FDA Link
01/2019
1Therapeutic UsesIBA
01/2019
1DNA (Deoxyribonucleic Acid)IBA
01/2018
1MicroRNAs (MicroRNA)IBA
01/2017
1Member 11 Subfamily B ATP Binding Cassette TransporterIBA
10/2016
1Dacarbazine (DIC)FDA LinkGeneric
10/2016
1Testosterone (Sustanon)FDA Link
01/2016
1Vitamin A (Retinol)FDA LinkGeneric
01/2016

Therapy/Procedure

11Therapeutics
01/2022 - 03/2006
4Drug Therapy (Chemotherapy)
01/2020 - 09/2005
2Enteral Nutrition (Feeding, Tube)
03/2008 - 09/2005
1Polypharmacy
01/2020